Direct Phasing and Structure Determination of Macromolecules Using Single Wavelength Anomalous Scattering (SAS) of Sulfurs in the Native Crystals
نویسندگان
چکیده
CRYSTAL STRUCTURE AND MUTATIONAL ANALYSIS OF AMINOACYLHISTIDINE DIPEPTIDASE FROM VIBRIO ALGINOLYTICUS REVEAL A NEW ARCHITECTURE OF M20 METALLOPEPTIDASES Chin-Yuan Chang, Yin-Cheng Hsieh, Ting-Yi Wang, Yi-Chin Chen, Yu-Kuo Wang, Ting-Wei Chiang , Yi-Ju Chen, Cheng-Hsiang Chang, Chun-Jung Chen*, and Tung-Kung Wu* Department of Biological Science and Technology, National Chiao Tung University, Hsinchu 30010, Taiwan; Life Science Group, Scientific Research Division, National Synchrotron Radiation Research Center, Hsinchu 30076, Taiwan; Institute of Bioinformatics and Structural Biology, Department of Physics National Tsing Hua University, Hsinchu 30013, Taiwan; Institute of Biotechnology, National Cheng Kung University, Tainan 701, Taiwan Running head: Crystal structure of V. alginolyticus PepD Address correspondence to: Tung-Kung Wu, 75, Po-Ai Street, Hsin-Chu 30010, Taiwan, R.O.C., Fax: +886-3-572-5700; E-mail: [email protected]; Chun-Jung Chen, 101 Hsin-Ann Road, Hsin-Chu 30076, Taiwan, R..C., Fax: +886-3-578-3813; E-mail: [email protected]
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